Virgin Atlantic has San Francisco to Manchester, UK Business Class tickets for $2,002 round trip on nonstop flights with lie flat seats for travel through end of schedule including peak summer and Christmas season dates.
Lowest priced tickets are on Delta Airlines with codeshare flights. Some itineraries route via Delta flights to New York JFK for Virgin Atlantic flight.
Delta Airlines Business Class ticket for Virgin Atlantic operated flights
San Francisco SFO – Manchester MAN – San Francisco SFO
Delta Airlines Business Class ticket for Delta (SFO-JFK) and Virgin Atlantic operated flights (JFK-MAN).
San Francisco SFO – New York JFK – Manchester MAN – New York JFK – San Francisco SFO