AeroMexico has one of the lowest fares at $634 to $654 I’ve seen over the past year for travel from Los Angeles LAX or San Francisco SFO to Santiago, Chile SCL. These are one-stop flights via Mexico City with the option to layover for four to five hours at $654 or a cheaper option to spend the day in Mexico City with an 18 hour layover on a $634 round trip fare.
Low fares are available most dates in April and May 2016. Google Flights shows $582 fares, however, these rise to $634 and $654 once return date is selected.
American Airlines offered this route for $643 round trip, for a brief purchase period one month ago, routing via Miami.
AeroMexico Los Angeles LAX – Mexico City MEX – Santiago SCL Chile
$653.76 (Priceline) Sunday April 10 – Saturday April 16
AeroMexico is a SkyTeam Alliance airline member. Delta SkyMiles members earn 50% redeemable miles for AeroMexico Economy E and V class, 100% MDM and 10% MDQ.
Loyalty Traveler – American $643 LAX to SCL Santiago Chile (Feb 9, 2016).